Tissue Bank In the Stanford Cancer Institute

Virtual Bank

The Stanford Tissue Bank provides a portal to the following more specialized tissue repositories accessible to Stanford investigators:

Leukemia bank: managed by Dr. Jason Gotlib ( ), Dept. of Medicine-Hematology. This repository includes cryopreserved cells from peripheral blood and bone marrow specimens including leukemias, myelodysplasias and myeloproliferative disorders.

Lymphoma bank: managed by Dr. Ronald Levy ( ), Dept. of Medicine-Oncology. This repository includes frozen tissues, cryopreserved cells and paraffin blocks from lymphoma specimens representing all major diagnostic categories of lymphoma.

Bone marrow transplant (BMT) bank: managed by Dr. David Miklos ( ), Dept. of Medicine-BMT. This repository includes both pre- and post-transplant peripheral blood and bone marrow specimens from patients with multiple myeloma, acute leukemia, chronic myeloid leukemia, myelodysplastic syndrome and non-Hodgkin’s lymphoma.

Histocompatibility Lab: managed by Dr. Dolly Tyan ( ), Dept. of Pathology. This repository includes DNA specimens isolated from residual blood, bone marrow, and lymph node material from recipients and donors for hematopoietic cell transplant, renal transplant and cardiac transplant, as well as pre-transplant sera from renal and cardiac transplant patients.

Neurosurgical tissue bank: managed by Dr. Hannes Vogel ( ), Dept. of Pathology. This repository includes both benign and malignant CNS specimens.

Northern California Cancer Center (NCCC): managed by various investigators at the NCCC; contact is Dr. Dee West ( ). Among its many repositories, the NCCC is one of six centers comprising the Breast Cancer Family Registry, which has banked clinically-annotated tumor blocks as well as genomic DNA from probands and family members. Specimens are available to Stanford investigators through approval of submitted requests, evaluated by an advisory committee for scientific merit and appropriate use of resources.

Locating Banked Biospecimens

The STRIDE Anonymous Biospecimen Locator allows Stanford researchers to search the STRIDE Virtual Biospecimen Bank for suitable samples without having to know, or expose, any protected patient-specific information. Having determined that suitable specimens exist in one of the constituent biospecimens banks, the researcher can generate a Web-based request form to obtain additional information from the appropriate bank operator(s).

The first biospecimen bank searchable using this tool is the Stanford Cancer Center Pathology Core Tissue Bank, directed by Jonathan Pollack MD, PhD. Additional biospecimen banks are being added to STRIDE for searching by the system.

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